Arizona Cardinals vs Buffalo Bills Match Player Stats

The Arizona Cardinals vs Buffalo Bills match player stats always capture the attention of football fans, analysts, and fantasy football enthusiasts. Whenever these two teams collide on the gridiron, the game becomes more than just a competition — it turns into a showcase of elite talent, coaching strategies, and individual brilliance. Both franchises have strong histories, dynamic rosters, and players who deliver memorable performances under pressure.
We take a closer look at the player stats from the Arizona Cardinals vs Buffalo Bills matchup, analyzing offensive weapons, defensive standouts, and the overall impact of key contributors on the field.
Quarterback Duel: Kyler Murray vs Josh Allen
No discussion of the Cardinals vs Bills player stats is complete without examining the quarterback battle.
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Kyler Murray (Arizona Cardinals)
Murray’s dual-threat capability makes him one of the most dangerous quarterbacks in the league. Against the Bills, Murray’s stats often reflect his ability to extend plays outside the pocket, making key throws under pressure, and using his legs to convert crucial first downs. His passing yards typically hover in the mid-200s during such matchups, paired with rushing totals that can easily exceed 50 yards. In addition, Murray’s red-zone awareness and connection with his wide receivers are vital when the Cardinals face a tough Buffalo defense. -
Josh Allen (Buffalo Bills)
On the other side, Josh Allen continues to prove why he is one of the most elite quarterbacks in the NFL. Known for his cannon-like arm and physical rushing style, Allen’s stats in this matchup often surpass 300 passing yards with multiple touchdowns. His completion rate against Arizona varies depending on the Cardinals’ defensive schemes, but Allen’s ability to push the ball deep downfield creates explosive plays. Adding in his rushing yards — often 30 to 60 per game — Allen consistently gives the Bills a statistical advantage.
When comparing these two quarterbacks, the player stats show a thrilling contrast of styles: Murray relies on quickness and creativity, while Allen thrives on power and aggressiveness.
Wide Receivers and Playmakers
The Arizona Cardinals vs Buffalo Bills match player stats highlight some of the league’s best wide receivers.
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Arizona Cardinals Receivers
The Cardinals have long benefited from star receivers. DeAndre Hopkins, for example, has often dominated the stat sheets against Buffalo with receptions ranging from 8–10 catches and over 100 receiving yards. His famous “Hail Murray” catch in 2020 against the Bills remains one of the most iconic plays in NFL history. Additionally, younger talents and secondary targets such as Rondale Moore and tight end Trey McBride have contributed with crucial receptions, extending drives and keeping defenses guessing. -
Buffalo Bills Receivers
The Bills, of course, counter with their own stars. Stefon Diggs has been Allen’s most reliable weapon, posting stats that often surpass 100 yards receiving in big matchups. His route-running precision and ability to find separation make him a nightmare for Arizona’s secondary. Complementing Diggs, players like Gabe Davis bring deep-threat potential, often recording long touchdown catches that inflate the Bills’ offensive numbers.
The stat sheets consistently show that both teams thrive on big passing plays, making the wide receiver battle one of the most exciting aspects of this matchup.
Running Game Impact
While both teams are known for their passing, the running backs’ stats still play a critical role.
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Arizona Cardinals: James Conner often carries the load for Arizona’s backfield. In games against Buffalo, his rushing yards range between 70–100 when the offensive line establishes control. Conner also contributes as a pass-catching option, adding receptions to his stat line and providing balance against an aggressive Bills defense.
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Buffalo Bills: Devin Singletary and, more recently, James Cook, provide versatility in the Bills’ ground attack. Their rushing totals often complement Allen’s scrambling ability. In addition, they contribute in the receiving game, with Cook averaging multiple catches and significant yards after the catch.
Player stats highlight that while neither team is run-heavy, their backs are crucial for short-yardage conversions and red-zone scoring opportunities.
Defensive Standouts
When reviewing the Cardinals vs Bills defensive stats, certain names frequently stand out.
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Arizona Cardinals Defense
Budda Baker, the Cardinals’ star safety, is often at the center of their defensive efforts. His stats include high tackle counts, pass deflections, and occasionally interceptions. Linebackers such as Zaven Collins add pressure on quarterbacks, while the Cardinals’ pass rush looks to disrupt Josh Allen’s rhythm. -
Buffalo Bills Defense
The Bills counter with their own defensive stars. Tre’Davious White (when healthy) provides elite coverage, limiting Arizona’s top receivers. Linebackers like Matt Milano contribute with high tackle numbers and blitz effectiveness. Defensive linemen such as Ed Oliver bring interior pressure, forcing quarterbacks into hurried throws.
The defensive stats show that both units look to create turnovers and capitalize on momentum swings, which often become deciding factors in close matchups.
Special Teams and X-Factors
Player stats also reveal the hidden contributions from special teams. Kickers like Tyler Bass (Bills) and Matt Prater (Cardinals) are often consistent, adding crucial field goals that swing momentum. Return specialists and coverage units also make subtle yet important statistical contributions.
Coaching decisions and time management often amplify how player stats translate into real outcomes. For example, red-zone efficiency, third-down conversions, and penalties directly shape the flow of the game.
Read More: Chicago Bears vs Houston Texans Match Player Stats
Conclusion
The Arizona Cardinals vs Buffalo Bills match player stats reflect more than just numbers on a sheet — they tell the story of two competitive teams bringing out the best in each other. From Kyler Murray’s dynamic scrambles to Josh Allen’s explosive deep passes, from Hopkins’ clutch catches to Diggs’ game-changing routes, every matchup creates a statistical narrative that excites fans and analysts alike.
In the end, the stats highlight the balance of skill, preparation, and execution. Whether it’s offense lighting up the scoreboard or defenses stepping up with key stops, the Cardinals vs Bills rivalry continues to deliver memorable moments for the NFL community.



